BOWEL DISEASE RESEARCH FOUNDATION of The Association of Coloproctology of Great Britain and Ireland Advancing the cure and treatment of bowel disease

The management of malignant large bowel obstruction: ACPGBI position statement.

Which is the optimal bowel preparation for colonoscopy - a meta-analysis.

OBJECTIVE To assess which bowel preparation agent is most effective. METHODS A search of randomized trials between January 1990 and July 2005 was obtained, using MEDLINE and PubMed databases, and the Cochrane Central Register of Controlled Trials. Meta-analysis was performed using the Forest plot review. RESULTS Sodium phosphate (NaP) was more effective in bowel cleansing than polyethylene ...

Anorectal manometry with water-perfused catheter in healthy adults with no functional bowel disorders.

Anorectal manometry provides an objective assessment of anal sphincter pressure and rectal sensitivity and anorectal reflexes in response to distension. However, its clinical utility is hampered by a lack of standardized protocols and normative data from healthy subjects. Previous studies have used water-perfused systems in normal subjects, but some adopted a rapid pull-through technique; other...

Online-Only Abstracts.

A. Hotouras*†, Y. Ribas‡, S. A. Zakeri†, Q. M. Nunes§, J. Murphy¶, C. Bhan† and S. D. Wexner** *National Centre for Bowel Research and Surgical Innovation, †Department of Surgery, Whittington Hospital NHS Trust, London, UK, ‡Department of Surgery, Consorci Sanitari de Terrassa, Terrassa (Barcelona), Spain, §NIHR Liverpool Pancreas Biomedical Research Unit, Royal Liverpool and Broadgreen Univers...

Application of extracellular vesicles in the treatment of inflammatory bowel disease

Introduction: Inflammatory bowel disease(IBD) is caused by genetic, environmental, microbial and immune factors. IBD has two primary forms: Ulcerative colitis and Crohn´s disease. The incidence of IBD has significantly increased over the last few decades. Given that patients have poor response to drug treatments or are resistant to drug therapies, new therapies are needed for gastrointestinal i...